Anti-aging Therapies
We have a Multi-factorial approach to living a healthier life, and prevent or postpone degeneration and loss of function.
Supplements:
We generally recommend the evolving and evidence-based advice of Dr David Sinclair. He is an anti-aging expert and professor at Harvard University. He has been studying aging for the better part of his academic career.
Dr. David Sinclair's main research interest is the epigenetics of aging with a focus on epigenetic reprogramming of aging, NAD+ metabolism and sirtuins, and NAD+ precursors like NR and NMN
NAD+ (nicotinamide adenine dinucleotide) is a vital molecule found in every cell that plays a central role in energy production and cellular repair. As we age, NAD+ levels naturally decline, which contributes to reduced mitochondrial function, DNA damage accumulation, and impaired cell repair. Supporting NAD+ levels helps activate sirtuins (proteins linked to longevity), improve mitochondrial efficiency, and enhance cellular resilience. This can slow age-related decline, promote healthier metabolism, and support overall anti-aging processes at the cellular levels
You may have come across his published, New York Times best-selling book on aging, Lifespan: Why We Age And Why We Don't Have To.
Here is a good summary of his recommendations, we provide a more limited set of recommendations that we believe are easier to comply with:
Core Supplements:
- Resveratrol: 1 gram per day
- Nicotinamide Mononucleotide (NMN): 1 gram per day
- Metformin: 800-1000 (tel:800-1000) mg per day
- Vitamin D3: 4000-5000 (tel:4000-5000) IU per day
- Vitamin K2: 180-360 mcg per day
Additional Supplements:
- Spermidine: 1-2 mg per day
- Trimethylglycine (TMG): 500-1000 mg per day
- Quercetin: 500 mg per day
- Fisetin: 500 mg per day
- L-Taurine: 2 grams per day
- Low-dose aspirin: 81 mg per day
Diet:
We recommend a Mediterranean Diet. It focuses on plant-based foods like vegetables, fruits, whole grains, legumes, and nuts, with olive oil as the main source of fat. Fish and seafood are eaten regularly, poultry and dairy in moderation, and red meat and sweets only occasionally.
This balance provides healthy fats, antioxidants, and fiber that support heart health, lower inflammation, improve blood sugar control, and reduce the risk of chronic diseases such as cardiovascular disease, type 2 diabetes, and certain cancers. It's also linked to longer lifespan and better cognitive function.
Peptides:
Depending on your goals, various peptides are available to aid in your journey for continued good health. Peptides can be administered as pills, troches, nasal spray or injection depending on how they are best absorbed.
Peptides can assist in different ways . Some by stimulating the natural release of growth hormone from the pituitary gland. Increased growth hormone levels support cellular repair, muscle maintenance, fat metabolism, and collagen production, which can improve skin elasticity, energy levels, sleep quality, and overall vitality. This helps counteract some of the natural declines associated with aging.
A peptide plan will include a choice of peptides that are cycled at 2-3 month intervals to prevent habituation and allow them to continue to work for you.